Quantification of bone strontium levels in humans by in vivo …
The need for in vivo bone strontium assessment arises because strontium may exert a number of effects on bone, which may be either beneficial or toxic. …
Bone Radionuclide Imaging, Quantitation and Bone …
Radionuclide bone imaging is a common investigation performed in most nuclear medicine departments. In early days, 87mSr was the bone agent used and interest in 99mTc for Nuclear Medicine imaging began in the early 1960's. The first technetium labelled bone agent, 99mTc-polyphosphate, was described by Subramanian and McAfee …
Calibration of the 125I-induced x-ray fluorescence
1078 Keywords: strontium, bone, in vivo, x-ray fluorescence, coherent scatter, Monte Carlo (Some figures may appear in colour only in the online journal) 1. Introduction The calibration of in vivo x-ray fluorescence systems (IVXRF) of bone metal quantification are heavily dependant on a coherent normalization procedure as central to …
Monitoring bone strontium levels of an osteoporotic subject
A previously developed in vivo X-ray fluorescence (IVXRF) I-125 based system was used to measure bone strontium levels non-invasively in an osteoporotic volunteer. The volunteer was recruited in December 2008, as part of the Ryerson and McMaster University Strontium in Bone Research Study and …
Monitoring bone strontium levels of an osteoporotic …
22549020. . DOI: . 10.1016/j.bone.2012.04.008. . Abstract. . A previously developed in vivo X-ray fluorescence (IVXRF) I-125 based system was used to measure bone strontium …
The ratio of barium to strontium as a paleodietary indicator …
Males were intermediate. Gender differences in bone strontium among prehistoric human populations are considered in these terms. Download Free PDF View PDF. Free PDF. ... We present the first measurement of bioavailable strontium (87Sr/86Sr) and lead (206Pb/204Pb, 207Pb/204Pb, and 208Pb/204Pb) isotope ratios from five cattle bones …
Evaluation of bone strontium as a measure of seafood …
The recognition that bone strontium/calcium ratios reflect dietary levels of strontium and that seawater has a high strontium content led some archaeologists to infer that seafood consumption produces high Sr/Ca ratios in bone. Analyses of seawater and of marine organisms reveal, however, a marine trophic effect comparable to the trophic …
Quantification of bone strontium levels in humans by in …
The need for in vivo bone strontium assessment arises because strontium may exert a number of effects on bone, which may be either beneficial or toxic. Measurements discussed here are noninvasive, no sample is taken, nor is there discomfort to patients. The developed source excited x-ray fluorescence system employs a source to …
Evaluation of Strontium Interference in Calcium Measurement …
Background Bone health supplements containing strontium are available without prescription, however, the effects of strontium interference on clinical laboratory calcium measurement procedures are ...
Evaluation of geometries appropriate for 125I in vivo bone strontium …
We acquired in vivo measures of bone strontium in each rat using a custom X-ray fluorescence spectroscopy system [35,36,38, 41] at baseline, and 4 and 8 weeks after the start of dosing as ...
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Measurement of bone strontium (Sr) is vital to determining the effectiveness of Sr supplementation, which is commonly used for the treatment of osteoporosis. Previous technology uses radioisotope sources and bulky equipment to measure bone Sr.
Noninvasive Measurement of Bone Strontium
A previously developed in vivo X-ray fluorescence (IVXRF) I-125 based system was used to measure bone strontium levels non-invasively in an osteoporotic volunteer. The volunteer was recruited in December 2008, as part of the Ryerson and McMaster University Strontium in Bone Research Study and measured at twice …
In vivo study of an x-ray fluorescence system to detect bone strontium
An x-ray fluorescence (XRF) system using 125I as the source was developed to measure strontium in bone in vivo. As part of an in vivo pilot study, 22 people were measured at two bone sites, namely the index finger and the tibial ankle joint. Ultrasound measurements were used to obtain the soft tissue thickness at each site, which was …
Quantitative bioanalysis of strontium in human serum by …
Exposure to elevated levels of strontium during bone development has demonstrated toxicity. In a region with high prevalence of rickets, a correlation was seen with strontium rich soil and vegetable nutrition. ... in a recent method validation study to measure strontium levels in serum using ICP-MS. A mean value of 50.5 ± 6.4 ng/ml (n = 12 ...
EANM guidelines for radionuclide therapy of bone metastases …
The goals of these guidelines are to assist nuclear medical practitioners in: 1. Evaluating patients who might be candidates for treatment of metastatic bone pain using beta-emitting radionuclides such as strontium-89 (89 Sr, approved in Europe and the US), samarium-153 (153 Sm) lexidronam (153 Sm-EDTMP, approved in Europe and the US), …
Facts About Strontium | Live Science
Scientists measure the levels of strontium isotopes Sr-86 and Sr-87 in ancient teeth, bones or seashells, and then they compare the ratio of these two isotopes — either to one another or to ...
Effect of Bone Strontium on BMD Measurements
If we parameterize the effect of bone strontium content on BMD by assuming that substituting a molar fraction of the bone calcium by strontium causes the BMD measurement to change from, we obtain the following relationship for the strontium ratio. QCT scans measure volumetric bone density (g/cm) rather than areal bone density …
Quantification of bone strontium levels in humans …
Quantification of bone strontium levels in humans by in vivo x-ray fluorescence. The need for in vivo bone strontium assessment arises because strontium may exert a number of …
Accumulation of bone strontium measured by in vivo XRF …
An x-ray fluorescence (XRF) system using 125I as the source was developed to measure strontium in bone in vivo. As part of an in vivo pilot study, 22 people were measured at two bone sites, namely ...
Monitoring bone strontium levels of an osteoporotic
An in vivo X-ray fluorescence I-125 system was used to measure bone strontium levels non-invasively in an osteoporotic . We show bone strontium levels over a period of 2.5 years at cortical (finger) and trabecular (ankle) bone. The intriguing results show bone strontium incorporation and retention follow a pattern. Results …
Spectrometry methods for in vivo bone strontium measurements
In the case of a bone strontium measurement, commercial poP has been shown to contain rather large levels of strontium contamination, resulting in the inability to produce a true blank phantom and ...
(PDF) Evaluation of imaging technologies to correct for …
XRF measures of bone strontium content are influenced by soft tissue mass and bone geometry [35,36,42, 43]. Soft tissues can attenuate strontium X-rays, and differences in bone shape and size can ...
The Use and Abuse of Trace Elements for Paleodietary …
STRONTIUM AS A MEASURE OF THE PLANT/MEAT RATIO Omitting elements other than Ba and Sr as direct paleodietary indicators is critically necessary, but is not, in itself, sufficient. A second significant misstep in trace-element research was inferring that bone strontium is a proxy for the dietary plant/meatratio.
Accumulation of bone strontium measured by
The bone strontium measures are dimensionless values calculated from the strontium Kα peak counts and normalised to the 125 I coherent peak counts. At …
The Influence of Strontium on Bone Tissue …
It turns out that this effect is demonstrated by strontium ions, an element showing physical and chemical similarity to calcium, the basic element that builds the …
(PDF) The hydroxyapatite crystal: A closer look
Secondary outcome measures included femoral BMD, incidence of new vertebral deformities, and biochemical markers of bone metabolism. Lumbar BMD, adjusted for bone strontium content, increased in a ...
Strontium, Chemical Element
For instance, strontium-90 is used to measure the density of silk and tobacco products. Strontium-90 has medical applications. A recent advance is to use the isotope for the control of pain. People who have cancer of the bone often experience terrible pain. At one time, the only treatment was medication.
Noninvasive Measurement of Bone Strontium
The strontium content of bone has hitherto been impossible to measure noninvasively. A novel dual-photon absorptiometry (DPA) method was developed. 241 …
Why Strontium Is Not Advised for Bone Health
(Strontium may remain in the bones for as long as 7–10 years after the last dose.) Strontium has a chemical similarity to calcium and will replace calcium as the mineral in bone. ... "Currently, we do not …
THE CHARACTERIZATION OF BIOLOGICALLY AVAILABLE …
plants and animals are variable; and (2) a range of values in human bone and enamel data make it difficult to distinguish some migrants from locals. Analysis of the bones of small animals provides a robust measure of local strontium isotope ratios and a reliable, if con-servative, means for determining confidence limits for distinguishing ...
